Poloxamer basf pdf creator

Currently, excipientgrade poloxamer 188 nf, marketed by basf under the kolliphor p188 brand, is a polymer used in a variety of. It potentially has clinical utility in diverse diseases, such as acute myocardial infarction, acute limb ischemia, shock, acute stroke, heart failure, and sickle cell crisis. Is determined by the chain length of the polyethylene eo units and polyoxypropylene po. Pdf poloxamer gels are conventionally prepared by the hot or the cold process. Dual phase eye make up remover ec1 this dual phase formulation blends together to remove all eye make up, including waterproof. They make this highlyefficient intermediate, used in many types of applications, significantly easier and safer to handle. It is a surfactant functioning both as cleansing and solubilizing agent. Poloxamer hydrogels use in drug release appeared at the beginning of the 1970s.

For more information about basf s north american operations, visit. Basf engineering plastics offer decisive advantages over established metal structures in many areas. Serasense sf 2 dimethicone cleanses oils away, whilst serasense cf cpm caprylyl methicone smoothes the eye area without tackiness. Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol peg. Poloxamer p407based ampbcontaining polymeric micelles administered by subcutaneous injections in murine models will turn into a semirigid gel, when in contact with the local tissue, creating a reservoir system and keeping the drug in the extracellular space, then allowing its action against the parasites in the local infection site. Basf offers wide range of excipients for topical formulations enabling you to create the ideal skin delivery solution for your foam formulation. Elastollan tpu technical data sheet elastollan 1185a polyetherbased grade elastollan 1185a is specifically formulated for extruded profile, sheet and film applications. Basf corporation evaluation of lutrol f grades prill vs. By listening to our customers and working closely with them we are able to introduce new and exciting products and develop specific solutions for the most efficient and costeffective concrete production. Poloxamer 407 p407 and 188 p188 were obtained from basf co.

The common available grades are poloxamer 68, 88, 98, 108, 124, 188, 237, 338, and 407. Poloxamer 407mediated alterations in the activities of enzymes regulating lipid metabolism in rats. This section showcases our global product portfolio only. Information material on polyurethane products and systems. Nov 17, 2014 commercial grades nonproprietry name commercial grades poloxamer 124 l44 poloxamer 184 l64 poloxamer 185 p65 poloxamer 188 f68 poloxamer 237 f87 poloxamer 338 f108 poloxamer 407 f127 24. Additionally, poloxamer was found to mediate tablet dissolution on stability as. Poloxamer 407 is a hydrophilic nonionic surfactant of the more general class of copolymers known as poloxamers. Narayan1 1technical service, basf corporation, roxbury, nj, 2pharmaceutical marketing, basf corporation, mount olive, nj. Pdf poloxamers, poloxamines and polymeric micelles. You can find detailed information on our product range by looking up your industry or using our product finder. The masterfiber product family comes with the master builders solutions technical support team from basf. Pdf development of poloxamer gel formulations via hot. Pdf development of poloxamer gel formulations via hotmelt. Poloxamer selfassembly in aqueous solutions poloxamers are available in a broad range of molecular weights and ppopeo ratios.

Poloxamer 188 chemical information, properties, structures, articles, patents and more chemical data. Sigmaaldrich offers a number of poloxamer 188 products. The company inge gmbh develops innovative ultrafiltration technologies used in the treatment of drinking water, process water, sea water and waste water. They are also used in topical dosage forms and rectal suppositories. You will then be directed to your local website with complete product information for your local needs. Wasan 1, ramaswamy subramanian, mona kwong division of pharmaceutics and biopharmaceutics, faculty of pharmaceutical sciences, university of british columbia, vancouver, british columbia, canada. To develop hplc methods for the quantitation of pluronic polymers, as both diluted and as a component in a fluoride mouth wash sample, using an hplc. Flexible packaging inks quality you can see, properties you can rely on flexible packaging inks page 2 flexible packaging inks quality you can see, properties you can rely on flexible packaging offers brand owners, retailers, and consumers many advantages including high graphic capability, light weight, and resealability along with moisture and aroma barrier properties that protect and extend.

A comparative evaluation of poloxamer 407 and oxidized. Assessment of transdermal penetration enhancement by topical pharmaceutical excipients using skin pampa method m. The range of applications for these intelligent plastic solutions extends far beyond automotive engineering and opens up significant development potential for the solar, construction and water industry. Basf corporation basf lumogen f violet 570 fluorescence curve run in acetone 0. Pdf on jul 15, 2014, daniel j burnett and others published. Poloxamer 407 pluronic f127based polymeric micelles for. Poloxamers are triblock copolymers of polyethylene oxide peo and. Basf poloxamers offer better solubilizing properties compared to hpmc, pvp. Tel 862164705533 adress xuhui district, shanghai caoxi yinhai building, a1207 room, no. Learn about poloxamer from patients first hand experiences and trusted online health resources, including dosage, side effects and interactions. Poloxamer 407 was a gift sample from basf corporation, mumbai. Through science and innovation we provide our customers with products to meet the current and future needs of business and society. With innovative products, global field support and industry leading technical expertise, basf mining solutions provides sustainable solutions which increase productivity, recovery and flexibility throughout the mining operations including leaching, solvent extraction, flotation, solidliquid separation and tailings management. At basf, we create chemistry for a sustainable future.

Basf to develop a high purity poloxamer for mast therapeutics. Poloxamerbased thermoreversible gel for topical delivery. Brochures intermediates for special applications basf. To find technical product information, drawings, and details please use the country locator below and select the region and country of your choice. It exhibits excellent abrasion resistance, toughness, transparency, very good low temperature flexibility, hydrolytic stability and fungus resistance. Development of poloxamer gel formulations via hotmelt extrusion technology article pdf available in international journal of pharmaceutics 53712 december 2017 with 655 reads. Basf is committed to providing the poloxamer kolliphor p 188 bio, which is.

Characteristics the character of each poloxamer in terms of. Poloxamer 184 poloxamer 184 is a polyoxyethylene, polyoxypropylene block polymer. For protection from shear stress, poloxamer 188 has a long publication history. Raw materialinci name % ww trade namesupplier function phase a. Pdf research for new therapies to treat diseases like cancer, it is one of the focus of health sciences. Kolliphor p 188 is an poloxamer that enables and enhances a wide range of. We combine economic success with environmental protection and social responsibility. Poloxamers are also known by the trade names synperonics, pluronic, and kolliphor. Poloxamer 407mediated alterations in the activities of. Assessment of transdermal penetration enhancement by topical. Basf report 2014 pdf download the entire basf report 2014 as a pdf. Basf is the first company in the world to offer triphenylphosphine tpp in the form of pellets.

Basf corporation was supported on a polystyrene divinyl benzene solid matrix xad4. Pdf multiblock poloxamer surfactants suppress aggregation. Check for a typo in the url, use the navigation or go to the site home. A nonionic surfactant that has general functionality of surfactant, emulsifier, solubilizer and stabilizer. Apr 27, 2018 they are used in pharmaceutical formulations as surfactants, emulsifying agents, solubilizing agent, dispersing agents, and as in vivo absorbance enhancers.

Differential effects of commercialgrade and purified. Content overview trade nameandchemistry basf pigment nomenclature focus portfolio industrial coatings. Used in toothpaste, whitening gels, mouthwash, sun and skin care applications. Pluracare l 64 is a copolymer of ethylene oxide and propylene oxide with an average molecular weight of 2,900. Information material on polyurethane systems and products basf. They make this highlyefficient intermediate, used in many types of. Quantitation of pluronics by high performance liquid. Because the lengths of the polymer blocks can be customized, many different poloxamers exist that have slightly different properties. Poloxamer complete drug information, side effects and. Pdf determining solubility parameters of poloxamers by. The word poloxamer was coined by the inventor, irving schmolka, who received the patent for these materials in 1973.